Iron overload was considered as a risk factor for osteoporosis. However, there have been no clinical studies concerning the association between iron stores and bone mineral density (BMD) in osteoporotic fracture women. From June 2010 to December 2014, 376 postmenopausal osteoporotic women with hip fracture were enrolled in this study. BMD in proximal femur sites and lumber vertebra were measured with dual-energy X-ray absorptiometry using the same equipment.  In addition, we collected body mass index, blood routine index, blood biochemical index, bone turnover markers, and iron metabolism index.  After the adjustment of confounding factors, results shown that serum ferritin was negtively correlated with the BMD in hip( r=-0.446，P＜0.01) and lumber vertebra ( r=-0.349，P＜0.01). Moreover, the ferritin was positively correlated with bone resorption maker β-CTX （r=0.166，P＜0.01）, whereas it was not associated with bone formation marker P1NP. In conlusion, the increase in ferritin could reduce the BMD of osteoporotic fracture women, and these might be ascribed to enhanced bone resorption.